Next Generation Iontophoresis Devices

next-generation-iontophoresis

This technology uses micro-electronic energy rather than needles which provides incredible results in the areas of:

DEP - Next-Gen Iontophoresis for Enhanced Delivery

Dermo-ElectroPoration® (DEP) – Next Generation Iontophoresis Technology

The DEP is the only Class II FDA-cleared biophysical alternative to injections that provides a transdermal infusion of high-weight molecular modalities without needles, pain, or downtime. The DEP uses state-of-the-art technology to safely and effectively replace needles in treatments that rely on sub-dermal injections with a precise and uniform application known as Predictive Permeation™.

No Pain. No Needles. No Downtime.

Dermo-ElectroPoration® safely promotes the transdermal delivery of both micro- and macromolecules (more than 800,000 Dalton) into the body at a depth of up to 5mm without modifying the ionic drug solution pH, as with traditional iontophoresis. Dermo-ElectroPoration® requires no pH compensation patch, driving gels, or pre-charged ions. Unlike traditional iontophoresis, there is no electrolysis reaction at the site of the electrodes. There is no degradation of the original molecule being delivered, meaning the active agent is distributed whole, and its positive and negative ions are delivered into the body.

Perfect For

Patient Benefits include:

Dermo-ElectroPoration® (DEP) is a patented, proprietary technology from Mattioli Engineering. It utilizes the skins water based “channels” to allow ionic drug solutions to penetrate due to controlled “electroporation-like” continuous reversed polarity electrical pulses. Because of this, Dermo-ElectroPoration® is able to control the average pulse value and vary the pulse shape according to the skin’s specific electrical impedance. Dermo-ElectroPoration® promotes the transdermal delivery of both micro- and macro molecules (more than 800,000Dalton) safely into the body without the need of modifying the ionic drug solution pH, as with traditional iontophoresis. Dermo-ElectroPoration® does not require a pH compensation patch, driving gels, or pre-charged ions.

Dermo-ElectroPoration® is the only transdermal delivery device FDA cleared for the local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections.

Unlike traditional iontophoresis, Dermo-ElectroPoration® does not have an electrolysis reaction at the site of the electrodes. There is no degradation of the molecule being delivered.This means that both positive and negative ions of the drug are delivered into the body – the drug is delivered as a whole. DEP (Dermo-ElectroPoration®) System is the new non-invasive, stand alone powered drug-delivery system. Dermo-ElectroPoration® increases the skin’s permeability by using the skin’s water based channels opened by a particular controlled current delivered to the patient, therefore allowing the substances to be absorbed by the hypodermis and muscle membranes.

The Benefits to You and Your Patients

Capability of Transdermal Delivery of ionic drug solution of macromolecules (greater than 800.000 Dalton).
Homogeneous drug delivered on the selected area.
Real-time control on the amount of drug to delivered.
Real-time patient's skin impedance measurement for successful drug delivery.
Drug administration in a timely manner to avoid waste of product with 100% protection against external agents.
No Electrolysis effect – No drug PH modification.
No need of pre-charged compounds/carrying gels/specific products or particular preparations.
Safe to use on all skin conditions and Fitzpatrick Scale skin types.
Easy to use patented proprietary technology.
Non invasive.
Electrical Current perception protected.
Users don't need to change their existing protocols.

Enhance your current cosmetic procedures.

No Anesthetic required.
Gain the ability to infuse a wide variety of modalities into different layers of the skin and Sub-Q for maximum efficacy.

DEP – Next Generation Iontophoresis