BioFusion Poly Peptide Restore Serum

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Poly-Peptide Serum –Summary

Key Ingredients & Functions:

Matrixyl 3000® (Palmitoyl Tripeptide-1 & Tetrapeptide-7)
- Boosts collagen and hyaluronic acid production
- Firm skin and reduce photo-induced aging
- Clinically shown to reduce wrinkle density by 33%
Argireline® (Acetyl Hexapeptide-8)
- Reduces muscle contraction by modulating SNARE complex
- ↓ Wrinkle length by 15.9%, ↓ wrinkle area by 62.8%
- Needle-free alternative to botulinum toxin
SNAP-8™ (Acetyl Octapeptide-3)
- Inhibits neurotransmitter release up to 43%
- ↓ Wrinkle depth up to 38%, ↓ roughness by 56% in 14–28 days
- Provides relaxed, smooth appearance
SYN-AKE™ (Dipeptide Diaminobutyroyl Benzylamide Diacetate)
- Mimics Waglerin-1 peptide from snake venom
- Temporarily reduces facial muscle contractions
- Fast-acting expression line smoother
Leuphasyl® (Pentapeptide-18)
- Targets expression lines in synergy with Argireline
- Reduces muscle micro tension and prevents wrinkle formation

Clinical Efficacy Highlights:

Up to 72% wrinkle depth reduction (SNAP-8)
Up to 62.8% reduction in wrinkle area (Argireline)
Visible results in as little as 7–14 days
Improves skin firmness, tone, and hydration

Use Positioning:

Ideal for advanced anti-aging protocols, wrinkle reduction regimens
Clinical alternative to injectables with synergistic peptide blend
Great for mature skin, post-treatment recovery, and as a skin booster

Instructions for Use:

Press gently into skin until absorbed. Suitable for morning or evening use; layer under moisturizer or SPF

Key Ingredient Breakdown Poly-peptide Serum

Active/Effective Level:
Trade Name	Common Name	INCI
Seamollient	Seaweed Extract	Water (Aqua), Chondrus Crispus Extract, Propylene Glycol, Citric Acid
Hyaluronic Acid	Hyaluronic Acid	Sodium Hyaluronate
Matrixyl 3000 MBAL (see additional info below)	Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7	Glycerin, Water (Aqua), Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
ARGIRELINE peptide solution NP	Acetyl Hexapeptide-8	Water (Aqua), Phenoxyethanol, Potassium Sorbate, Acetyl Hexapeptide-8

Marketing Level:
Trade Name	Common Name	INCI
Syn-ake®	Dipeptide Diaminobutyroyl Benzylamide Diacetate	Glycerin, Water (Aqua), Dipeptide Diaminobutyroyl Benzylamide Diacetate
SNAP-8 peptide solution C	SNAP-8 peptide	Water (Aqua), Caprylyl Glycol, Acetyl Octapeptide-3
Leuphasyl peptide solution	Pentapeptide-18	Water (Aqua), Glycerin, Caprylyl Glycol, Pentapeptide-18

SYN-AKE®

Syn-Ake® is a small synthetic peptide that helps reduce the appearance of wrinkles and laughter lines – as our skin gets older, the number of expression and laughter lines increases, along with crow’s feet and forehead wrinkles. SYN-AKE® relaxes the face, reducing wrinkles without losing the ability to help people express themselves. It’s fast-acting, long-lasting, and fully reversible. New studies have confirmed that when used earlier, SYN-AKE® helps delay wrinkle appearance, with age-freezing effects.

Matrixyl® 3000:

Application: Matrixyl® 3000 is a powerful anti-aging peptide complex composed of Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, designed to stimulate collagen production, improve skin elasticity, and reduce wrinkles. It activates extracellular matrix renewal and repairs damaged skin proteins, leading to smoother, firmer, and younger-looking skin. Clinical studies have demonstrated that Matrixyl® 3000 can reduce wrinkle depth by up to 45% and improve skin elasticity by 20% within weeks. This peptide is widely used in anti-aging serums, creams, and eye treatments, offering an effective solution for wrinkle reduction, hydration, and long-term skin rejuvenation.

Current Research: Matrixyl® 3000 is a next-generation peptide complex widely studied for its ability to counteract the visible signs of aging by promoting collagen synthesis and reducing inflammation. A combination of Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 works synergistically to repair and strengthen the skin’s extracellular matrix (ECM), making it a key ingredient in high-performance anti-aging skincare formulations.

Mechanism of Action: Collagen Synthesis and Skin Repair Aging leads to the degradation of collagen, elastin, and hyaluronic acid, resulting in wrinkles, sagging, and loss of skin elasticity. Matrixyl® 3000 counteracts this process through:

Palmitoyl Tripeptide-1 Functions as a messenger peptide, mimicking the body’s natural collagen breakdown fragments to stimulate fibroblast activity and increase collagen and elastin production. Palmitoyl Tetrapeptide-7 – Reduces inflammation and oxidative stress by inhibiting interleukin-6 (IL-6), a cytokine responsible for collagen degradation and premature skin aging.

Together, these peptides restore skin integrity, improve hydration, and promote firmness, reducing fine lines and wrinkles.

Clinical Studies and Efficacy Several clinical and in vitro studies have validated the anti-aging benefits of Matrixyl® 3000:

Reduction in Wrinkle Depth – A 12-week clinical study demonstrated that Matrixyl® 3000 reduced wrinkle depth by up to 45%, with a noticeable improvement in skin smoothness and elasticity. Enhanced Skin Hydration and Firmness – Participants using a 5% Matrixyl® 3000 formulation reported a 20% increase in skin elasticity and hydration, making the skin appear more youthful and plump. Long-Term Skin Regeneration – Continuous application was found to accelerate skin renewal and reinforce the skin barrier, leading to firmer, healthier-looking skin over time.

Comparison with Other Anti-Aging Peptides Matrixyl® 3000 is often compared to other collagen-boosting peptides, such as Matrixyl® (Palmitoyl Pentapeptide-4) and Palmitoyl Tripeptide-5. Unlike its predecessors, Matrixyl® 3000 offers collagen stimulation and anti-inflammatory benefits, making it more effective for mature and sensitive skin types.

Additionally, it differs from Argireline (Acetyl Hexapeptide-8), which reduces muscle contractions to prevent dynamic wrinkles. Instead, Matrixyl® 3000 targets structural wrinkles and collagen loss, making it ideal for firming and repairing aging skin.

Future Research and Applications Ongoing studies are exploring Matrixyl® 3000 in combination with hyaluronic acid, niacinamide, and antioxidants to enhance skin hydration, firmness, and repair. Researchers are also investigating its potential in wound healing and post-inflammatory skin recovery.

With its proven ability to reduce wrinkles, improve skin elasticity, and promote long-term rejuvenation, Matrixyl® 3000 remains one of the most effective peptides in anti-aging skincare, particularly in serums, creams, and eye treatments targeting mature and aging skin.

Argireline Peptide:

SNAP-8 peptide:

Clinically Proven Peptides. Visible Anti-Aging Results.

Our Poly-Peptide Serum delivers cutting-edge peptide technology to target fine lines, expression wrinkles, and skin roughness — without injections.
Backed by clinical data, this formula helps relax facial tension, stimulate collagen, and reveal smoother, younger-looking skin in just weeks.