The Power of Stem Cells
Stem cells play a significant part in the growth of multi-cellular organisms. Beginning with prenatal development, the three to five-day-old embryo known as the blastocyst contains stem cells within its foundation that give rise to the organism’s entire body. This includes organs such as the heart and lungs, multiple specialized cell types and other tissues. There are discrete populations of stem cells in some adult tissues such as muscle and bone marrow that regenerate cells lost through injury, illness and gradual wear.
While stem cells are more abundant in embryonic tissue and bone marrow, research from 2006 made a breakthrough in creating the conditions necessary to reprogram some adult cells to assume a state similar to stem cells. These are known as induced pluripotent stem cells (iPSCs) and have opened the door for regenerative medicine to continue expanding.
Laboratory studies have enabled scientists to utilize the essential properties of stem cells and analyze their functions in relation to other specialized cell types they can interact with. Research continues to advance as scientists make new discoveries on how stem cells not only develop an organism during prenatal growth but have their influence extend further into adulthood by growing and renewing cell populations as we age.
Although much progress remains to be made in screening stem cells for treating diseases, the regenerative capabilities of stem cells have the potential to reverse the debilitating effects of illnesses such as diabetes and heart disease, birth defects and other conditions. The prospects of healing tissue at a more effective rate through biological allografts derived from stem cells have provided promising and substantial results. At RegenOMedix, we pride ourselves on being an authority in reg
What is Regenerative Medicine?
Regenerative medicine oﬀers alternative solutions to costly surgeries and oﬀers hope for people with conditions that today are beyond repair.
Current Treatments Utilizing Regenerative Medicine
Osteoarthritis of the joints including knee, hip, shoulder and ankle joints
Chronic partial rotator cuﬀ tears, muscular tears, persistent partial tendon tears, such as tennis elbow, plantar fasciitis, quadriceps and patellar tendon tears
Meniscal (cartilage) tears in the knee, Sacroiliac joint pain, Chronic radiculopathy (pinched nerve), Discogenic back pain, Spinal facet pain
Aseptic processing is crucial for biologic-based products as we strive to maintain the viability of the cellular components, growth factors and protein messengers. Aseptic techniques are deployed to ensure the absence of pathogenic organisms so as to protect the patient from infection and to prevent the spread of pathogens. If during processing these cells were destroyed and the proteins denatured, they would no longer be viable and their usefulness would be negated.
In an aseptic process, the container/closure is subjected to sterilization methods separately, as appropriate, and then brought together with the biologic allograft. Because there is no process to sterilize the product in its final container, it is crucial the containers be filled and sealed under the most stringent aseptic technique possible.
The goal of aseptic processing is to minimize the risk of introducing any microbial contaminant into our product as it moves through the manufacturing process. We must be absolutely certain that there is no microbial contamination of the final sealed product. We utilize various approved techniques to ensure our allograft products are free of contaminants, thereby reducing the risk of infection to the patient.
Investigating the different types of stem cells
Induced pluripotent stem cells (iPSCs) are engineered in labs to reprogram tissue-specific cells to operate like embryonic stem cells. While iPSCs are designed to replicate the characteristics of embryonic stem cells such as giving rise to every cell type in the body, there are discrepancies between the two. Because iPSCs can be designated to serve a specific function, researchers are experimenting ways to fully convert iPSCs into a readily available source of stem cells for regenerative therapy. They are vital in helping researchers study the development of organisms, discovering how diseases progress and providing a basis for creating and testing new medical treatments.
Mesenchymal stem cells (MSCs) are stromal cells that are normally found in the bone marrow. However, MSCs can be grown from other tissue material as well such as cord blood, peripheral blood, fetal liver, lung, and fallopian tube. Because they are multipotent stem cells, they are capable of differentiating to form cell types like adipocytes, chondrocytes, osteocytes and cardiomyocytes. Their high capacity for self-renewal gives MSCs great potential for replacing or repairing damaged tissue such as bone, cartilage, muscle, tendons, and skin.