Introduction2018-12-27T17:46:05+00:00

RegenOMedix’ s goal is to inform you about allograft products as a substitute for traditional pain management and surgery. Not all the information here will apply to your individual patient’s treatment or its outcome. The information is intended to answer some of your questions and serve as a stimulus for you and your practice as a possible addition to your current therapies.

Types of Allografts we offer

Anu RHEO+

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Cord Blood

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EXOSOMES

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The Power of Stem Cells

With the strength, capabilities and adaptability of stem cells, RegenOMedix can help you tap into the body’s regenerative abilities. Stem cells serve as an internal repair system that replenishes cell counts as they divide and proliferate. As they divide, the new stem cells they produce can either remain as they are or shift into a more specialized function. From brain and muscle cells to red blood cells, the utility they have is indispensable for rebuilding cellular structures as they interact with tissue.

There are two distinctions that make stem cells unique: the ability to renew themselves and transform into other cells. After long durations of inactivity, stem cells are able to duplicate or evolve into specialized cells that assist in organ or tissue development under certain conditions. Particularly, when stem cells are located in organs such as the gut and bone marrow, they can regularly revitalize damaged or inadequate tissue during cell division.

Stem cells play a significant part in the growth of multi-cellular organisms. Beginning with prenatal development, the three to five-day-old embryo known as the blastocyst contains stem cells within its foundation that give rise to the organism’s entire body. This includes organs such as the heart and lungs, multiple specialized cell types and other tissues. There are discrete populations of stem cells in some adult tissues such as muscle and bone marrow that regenerate cells lost through injury, illness and gradual wear.

While stem cells are more abundant in embryonic tissue and bone marrow, research from 2006 made a breakthrough in creating the conditions necessary to reprogram some adult cells to assume a state similar to stem cells. These are known as induced pluripotent stem cells (iPSCs) and have opened the door for regenerative medicine to continue expanding.

Laboratory studies have enabled scientists to utilize the essential properties of stem cells and analyze their functions in relation to other specialized cell types they can interact with. Research continues to advance as scientists make new discoveries on how stem cells not only develop an organism during prenatal growth but have their influence extend further into adulthood by growing and renewing cell populations as we age.

Although much progress remains to be made in screening stem cells for treating diseases, the regenerative capabilities of stem cells have the potential to reverse the debilitating effects of illnesses such as diabetes and heart disease, birth defects and other conditions. The prospects of healing tissue at a more effective rate through biological allografts derived from stem cells have provided promising and substantial results. At RegenOMedix, we pride ourselves on being an authority in reg

What is Regenerative Medicine?

Regenerative medicine offers alternative solutions to costly surgeries and offers hope for people with conditions that today are beyond repair.

Current Treatments Utilizing Regenerative Medicine

Osteoarthritis of the joints including knee, hip, shoulder and ankle joints

Chronic partial rotator cuff tears, muscular tears, persistent partial tendon tears, such as tennis elbow, plantar fasciitis, quadriceps and patellar tendon tears

Meniscal (cartilage) tears in the knee, Sacroiliac joint pain, Chronic radiculopathy (pinched nerve), Discogenic back pain, Spinal facet pain

Aseptic Processing

Aseptic processing is crucial for biologic-based products as we strive to maintain the viability of the cellular components, growth factors and protein messengers. Aseptic techniques are deployed to ensure the absence of pathogenic organisms so as to protect the patient from infection and to prevent the spread of pathogens. If during processing these cells were destroyed and the proteins denatured, they would no longer be viable and their usefulness would be negated.

In an aseptic process, the container/closure is subjected to sterilization methods separately, as appropriate, and then brought together with the biologic allograft. Because there is no process to sterilize the product in its final container, it is crucial the containers be filled and sealed under the most stringent aseptic technique possible.

The goal of aseptic processing is to minimize the risk of introducing any microbial contaminant into our product as it moves through the manufacturing process. We must be absolutely certain that there is no microbial contamination of the final sealed product. We utilize various approved techniques to ensure our allograft products are free of contaminants, thereby reducing the risk of infection to the patient.

Investigating the different types of stem cells

Embryonic
Stem Cells

Embryonic stem cells are found within the blastocyst, a structure that forms within three to five days after fertilization and contains an inner mass that hosts stem cells. During prenatal development, cells inside of a blastocyst can give rise to specialized cells that work to create the tissue and organs that make up the entire body. When extracted from the blastocyst and grown under certain conditions in a laboratory, these cells retain their properties as embryonic stem cells. As pluripotent cells, they are self-renewing and capable of producing any cell type or tissue the body needs for regenerative healing. They are highly valuable because they offer a means for scientists to study cellular development and test new treatment options. The embryonic stem cells used in regenerative medicine are derived from blastocysts created through in vitro fertilization with informed consent from donors and are not taken directly from a woman’s body.

Tissue Specific
Stem Cells

Tissue-specific stem cells, known as somatic or adult stem cells, are more centered around specialization as they typically generate cell types based on the tissue or organ they originate from. As an example, blood-forming, hematopoietic stem cells found in the bone marrow can produce red and white blood cells and platelets, but cannot create cells for other parts of the body such as the lung, brain or liver. Similarly, stem cells constructed for other tissues and organs will not be able to generate blood cells or platelets. Tissue-specific stem cells do not self-renew as easily and can be difficult to find in comparison to embryonic stem cells. However, studies on tissue-specific stem cells have expanded our general knowledge of human development as they give us insight on how the body grows, ages and responds to injury and illness.

Induced Pluripotent
Stem Cells

Induced pluripotent stem cells (iPSCs) are engineered in labs to reprogram tissue-specific cells to operate like embryonic stem cells. While iPSCs are designed to replicate the characteristics of embryonic stem cells such as giving rise to every cell type in the body, there are discrepancies between the two. Because iPSCs can be designated to serve a specific function, researchers are experimenting ways to fully convert iPSCs into a readily available source of stem cells for regenerative therapy. They are vital in helping researchers study the development of organisms, discovering how diseases progress and providing a basis for creating and testing new medical treatments.

Mesenchymal
Stem Cells

Mesenchymal stem cells (MSCs) are stromal cells that are normally found in the bone marrow. However, MSCs can be grown from other tissue material as well such as cord blood, peripheral blood, fetal liver, lung, and fallopian tube. Because they are multipotent stem cells, they are capable of differentiating to form cell types like adipocytes, chondrocytes, osteocytes and cardiomyocytes. Their high capacity for self-renewal gives MSCs great potential for replacing or repairing damaged tissue such as bone, cartilage, muscle, tendons, and skin.